Coding

Part:BBa_K5310050:Design

Designed by: Elias Pilianidis   Group: iGEM24_thessaloniki   (2024-09-30)


MOG-CAAR-v1


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal PstI site found at 1548
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal PstI site found at 1548
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 643
    Illegal BglII site found at 1610
    Illegal XhoI site found at 1042
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal PstI site found at 1548
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal PstI site found at 1548
    Illegal NgoMIV site found at 777
    Illegal AgeI site found at 151
    Illegal AgeI site found at 1798
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

This design is the first version of our CAAR constructs with the role of recognising and binding to MS autoantibodies and producing an cell response.


Source

This part is a chimeric protein with domains from human proteins and a synthetic fusion linker between the extracellular and transmembrane parts.

References